Are there medications that can worsen symptoms?

Yes, there are medications that can exacerbate symptoms:

  • Antihistamines and tricyclic antidepressants: diminish the force of bladder muscle contraction
  • Decongestants (cold remedies): increase the contraction of the muscles that surround the neck of the bladder.
  • Diuretics: increase urine production.
  • Opiates: interfere with neuro-muscular mechanisms of urination